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以荧光染料BODIPY 为母体,通过柔性碳链分别连接三乙胺、三苯基膦及F16,合成得到了三种线粒体靶向荧光探针。通过MTT、Confocal、FL 及流式细胞仪等方法检测,对比了其荧光量子产率、细胞毒性、线粒体定位能力、细胞摄取速率等。
三种亲脂性阳离子线粒体靶向性能研究
【摘 要】
：
以荧光染料BODIPY 为母体,通过柔性碳链分别连接三乙胺、三苯基膦及F16,合成得到了三种线粒体靶向荧光探针。通过MTT、Confocal、FL 及流式细胞仪等方法检测,对比了其荧
【机 构】
：
武汉大学
【出 处】
：
中国化学会生物物理化学专业委员会第四届全国生物物理化学会议
【发表日期】
：
2016年期
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