The PHOENIX Study A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial of Ibrutinib Combined

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户：wanshixian

【摘要】

：

【作者】

：

Jun Zhu Tatsuo Ichinohe Hyeon Seok Eom Tsai-Yun Chen Kevin M.Bellew Steven Sun Jessica Vermeulen Sen Hong Zhuang Wyndham Wilson Anas Younes

【机构】

：

Beijing Cancer Hospital,Beijing,China Hiroshima U

【出处】

：

The 35th World Congress of the International Society of Hema

【发表日期】

：

2014年5期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Background Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous disease that can be classified by immunohistochemistry into 2 subgroups germinal center B-cell-like (GCB) or non-GCB (a subgroup including the activated B-cell-like subtype as well as some intermediate molecular subtypes).

其他文献

Methylation of CTNNA1 promoter frequent but not an adverse prognostic factor in acute myeloid leukem

Objective The reduced expression of CTNNA1 gene,a putative tumor suppressor gene,has been found in several cancers including acute myeloid leukemia (AML).CTNNA1 expression is regulated by methylation

会议

Prognostic impact of splenomegaly on survival of Chinese with primary myelofibrosis

Objective Predicting survival in persons with primary myelofibrosis (PMF) is typically based on the International Prognostic Scoring System (IPSS),the Dynamic IPSS (DIPSS) or the DIPSS-Plus.These scor

会议

Alcohol consumption and the risk of myelodysplastic syndromes a meta-analysis of epidemiological stu

Objective Previous reports regarding the association between alcohol intake and the risk of myelodysplastic syndromes (MDS) have been inconclusive.We conducted a meta-analysis to evaluate alcohol inta

会议

Aberrant hypermethylation of CTNNA1 gene is associated with higher IPSS risk in patients with myelod

Objective CTNNA1 gene is a putative tumor suppressor for its roles in inhibiting proliferation and promoting apoptosis.Aberrant expression of CTNNA1 is regulated by epigenetic mechanisms including bot

会议

Pesticide exposure as a risk factor for myelodysplastic syndromes a meta-analysis based on 1,942 cas

Objective Pesticide exposure has been linked to increase risk of cancer at several sites,but its association with risk of myelodysplastic syndromes (MDS) is still inconsistent.A meta-analysis of studi

会议

Study on myelodysplastic syndrome T lymphocyte immune abnormalities and cyclosporin A intervention t

Objective The myelodysplastic syndromes (MDS) constitute a group of heterogeneous clonal haemopoietic stem cell disorders,characterized by ineffective and dysplastic haematopoiesis with varying degree

会议

The use of FISH for detection of chromosomal abnormalities in myelodysplastic syndrome--A Prospectiv

Objective To evaluate the effect of FISH studies and conventional G-banding analysis in detecting chromosomal abnormalities in MDS patients.Methods 1132 bone marrow samples were obtained from 957 pati

会议

Artesunate induces apoptosis through caspase-dependent and-independent mitochondrial pathways in hum

Artesunate (ART) is a semi-synthetic derivative of artemisinin extracted from Artemisia annua (sweet wormwood) that is conventionally used in anti-malarial drugs and more recently in medications that

会议

Gene expression profiling in the myelodysplastic syndromes after SPARC overexpress and effect with A

SPARC plays key roles in erythropoiesis,haploinsufficiency of SPARC is implicated in the progression of the myelodysplastic syndromes,meanwhile the myelodysplastic syndromes (MDS)have no effective tre

会议

Amino acid residue E543 in JAK2 C618R is a potential therapeutic target for myeloproliferative disor

Janus kinase 2 (JAK2) is an important mediator of cytokine receptor signaling and plays a key role in the hematopoietic and immune responses.The acquired JAK2 C618R somatic mutation is detected in a s

会议

The PHOENIX Study A Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial of Ibrutinib Combined

其他学术论文