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  5. Characteristics and management of Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemase in a ter

Characteristics and management of Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemase in a ter

来源 :中华医学会第八次全国中青年检验医学学术会议 | 被引量 : 0次 | 上传用户：txzhang50
【摘 要】
：
Background The emergence of Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemases is rare but the consequences can be devastating.Aims We report an occurrence of Enterobacteriaceae harboring IMP-
【作 者】
：
Feng PANG Xiu-qin JIA Yan-hua LI Zhen-zhu SONG Qi-gang ZHAO 
【机 构】
：
Department of Clinical Laboratory,Liaocheng Peoples Hospital,Liaocheng,Shandong 252000,China
【出 处】
：
中华医学会第八次全国中青年检验医学学术会议
【发表日期】
：
2014年6期
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Background The emergence of Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemases is rare but the consequences can be devastating.Aims We report an occurrence of Enterobacteriaceae harboring IMP-4 or IMP-8 carbapenemases in a Chinese tertiary care hospital from November 2010 to December 2012.Methods The clinical characteristics of 30 patients were described.The infection control measures and the molecular investigations were reported.The genetic relatedness of isolates was determined by pulsed-field gel electrophoresis (PFGE).Carbapenemases were detected by modified Hodge test (MHT) and polymerase chain reactions (PCRs).Amplicons were sequenced and blasted to determine the genotype.
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