Neural interfaces with electrically controllable delivery of manganese ions applied for MEMRI-functi

• 作 者: Wei-ChenHuang[1]Yu-ChinLo[1]You-YinChen[2]San-YuanChen[1]
• 机 构: Department of Materials Science and Engineering,“National Chiao Tung University”,P.O.Box 30010,1001
• 出 处: The Third Symposium on Innovative Polymers for Controlled De
• 发表日期: 2014年期

　　Deep brain stimulation (DBS) is a well-developed neurosurgical technique for the treatment of numerous neurological disorders.It is important to understand the cerebral processes triggered by DBS [1].Manganese-enhanced MRI (MEMRI) allows non-invasive brain imaging through the uncoupling of brain activity.Based on the paramagnetic properties and the similarity to the calcium ions (Ca2+),Mn2+ accumulating in cells directly gives the responses to their activity via the MRI recording [2].