Surface Modified Ferritin Nanoparticles for Tumor Imaging and Drug Delivery

来源 :International Conference on Nanoscience & Technology,China 2 | 被引量 : 0次 | 上传用户：yusaihua

【摘要】

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【作者】

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Zipeng Zhen Wei Tang Hongmin Chen Xin Lin Trever Todd Geoffrey Wang Taku Cowger Xiaoyuan Chen Jin Xie

【机构】

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Department of Chemistry and Bio-Imaging Research Center (BIRC),University of Georgia,Athens,GA 30602

【出处】

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International Conference on Nanoscience & Technology,China 2

【发表日期】

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2013年3期

【关键词】

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ferritin drug delivery integrin αvβ3 nanocarrier doxorubicin

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　　Ferritin is a major iron storage protein found in humans and most living organisms.Each ferritin is comprised of 24 subunits, which self-assemble to form a cage-like nanostructure.In nature, the interiors of FRTs are filled with iron.When expressed artificially in an iron-free condition, the yielded apoferritins are hollow, comprising a cavity that can be loaded with different species.Ferritin nanocages can be genetically modified to present a peptide sequence on the surface.

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Surface Modified Ferritin Nanoparticles for Tumor Imaging and Drug Delivery

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