Correlation between the Degree of 6-Hydroxydopamine-Induced Dopaminergic Degeneration and In Vivo 99

来源 :华东六省一市生物化学与分子生物学会2015年学术交流会 | 被引量 : 0次 | 上传用户：zzzzkj

【摘要】

：

The 6-hydroxydopamine (6-OHDA)-induced rat model is widely used to evaluate nigrostriatal dopamine neuronal degeneration.The purpose of this study was to invest

【作者】

：

Ling Lin Jing Ye Han Zhang Shuiping Chen Zhihong Zheng

【机构】

：

ResearchCenterofNeurobiology,FujianMedicalUniversity,Fuzhou350108,China;DepartmentofBiochemistryandM

【出处】

：

华东六省一市生物化学与分子生物学会2015年学术交流会

【发表日期】

：

2015年12期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

The 6-hydroxydopamine (6-OHDA)-induced rat model is widely used to evaluate nigrostriatal dopamine neuronal degeneration.The purpose of this study was to investigate the association between the degree of 6-OHDA-induced dopaminergic degeneration and dopamine transporter (DAT) imaging using 99mTc-TRODAT-1 single-photon emission computed tomography (SPECT).The rats received different doses of unilateral 6-OHDA injection (2, 4, and 8 μg) into the right medial forebrain bundle.

其他文献

Hemibarbus maculates, microsatellite, wild population, hatchery population, genetic structure Spatia

Nucleotide sequences of the cytochrome b gene and D-loop control region of mitochondrial DNA (mtDNA) were used to assess the population genetic structure of Ony

会议

Hainan IslandOnychostoma lepturumphylogeographyS-DIVA

miR-451 negatively regulates hepatic gluconeogenesis by targeting glycerol kinase mediated glycerol

Type 2 diabetes (T2D) is characterized by insulin resistance and increased glucose production.microRNAS (miRs) have been identified as a new class of regulatory

会议

Structure-guided stereoselectivity inversion of a short-chain dehydrogenasereductase towards halogen

Stereoselectivity is one of the most significant properties of biocatalysts, which makes them the preferred choice in the biocatalysts-mediated asymmetric reduc

会议

E钙黏蛋白翻译后岩藻糖修饰调节肺癌细胞EMT

E-钙黏蛋白是一种上皮细胞标志蛋白,在上皮细胞的链接作用非常重要,在上皮细胞向间质细胞转化过程的过程中其表达水平改变显著,但是翻译后修饰对于E-钙黏蛋白的调节是否也会

会议

肺癌E-钙黏蛋白核心岩藻糖信号传导细胞迁移

Modulating Stat1 signaling by mitochondriai Tid1-a human homolog of bacterial DnaJ and the Drosophil

Human Tidl is a human homolog of bacterial DnaJ and the Drosophila tumor suppressor Tid56 that have two alternatively spliced isoforms Tid-Long and Tid-Short (T

会议

Human Tid1DnaJDnaKChaperoneJak2-Stat1 signaling

Human tumor suppressor hTid1-S, regulates AMPKmTOR signaling to suppress cell renal cell carcinoma p

Renal cell carcinoma (RCC) is the most common epithelial malignancy of the kidney in adults and accounts for approximately 3％ of adult malignancies and represent

会议

ccRCChTid1-Stumor suppressorAMPK/mTOR/JNK signalingOCR

Essential Roles of Mitochondrial Lon Protease in regulating cancer cell growth and cellular bioenerg

Mitochondria play a primary role in cellular bioenergetics in mosteukaryotic cells, which are responsible for producing nearly 95％ of cellular ATP through mitoch

会议

Lon proteasemitochondrialp53JNKROScellular bioenergetics

Tetramethylpyrazine blocks TFAM degradation and upregulates mitochondrial DNA copy number by interac

Protein quality control in mitochondria is essential for proper protein homeostasis, which maintains the mitochondrial function well and prevents the proteotoxi

会议

Downregulation of TFAM inhibits the tumorigenesis of non-small cell lung cancer by activating ROS in

Mitochondriai transcription factor A (TFAM), a member of high-mobility group (HMG) protein family encoded by the nuclear genome and transported into the mitocho

会议

mitochondriaTFAMnon-small cell lung cancerchemosensitivitycellular bioenerge

Isolation of H2S-tolerant methanotrophic bacteria for direct conversion of biogas to methanol from a

Biogas generated from anaerobic digestion (AD) systems is a renewable source of methane,but difficult to store and transport due to its gaseous form at ambient

会议

Correlation between the Degree of 6-Hydroxydopamine-Induced Dopaminergic Degeneration and In Vivo 99

其他学术论文