【摘 要】
：
组织光学参数测量是生物医学光子学主要研究内容之一,也为人体光学成像、成分光谱检测等提供研究基础.双积分球方法能够同时测量离体组织吸收系数、散射系数等,具有测准确、快速,适用范围大等优点,作为光学参数测量的标准方法得到广泛研究与应用.本文利用双积分球及超连续激光器搭建了宽光谱的组织光学参数测量系统,分析了积分球测量传递函数与误差来源及系统最佳测量条件,建立了基于BP-MCML的系统校正正向模型与L-
【机 构】
：
天津大学,精密仪器与光电子工程学院,天津300072;天津大学,精密测试技术及仪器国家重点实验室,天津300072
【出 处】
：
2014年全国博士后新材料技术与应用学术论坛
论文部分内容阅读
组织光学参数测量是生物医学光子学主要研究内容之一,也为人体光学成像、成分光谱检测等提供研究基础.双积分球方法能够同时测量离体组织吸收系数、散射系数等,具有测准确、快速,适用范围大等优点,作为光学参数测量的标准方法得到广泛研究与应用.本文利用双积分球及超连续激光器搭建了宽光谱的组织光学参数测量系统,分析了积分球测量传递函数与误差来源及系统最佳测量条件,建立了基于BP-MCML的系统校正正向模型与L-M算法的光学参数反构算法.在此基础上,测量了1100-1400nm连续宽谱范围内Intralipid溶液光学参数,实验结果表明改进后反构算法测量结果比较准确,多次测量标准偏差在3％以内,不同波长下约化散射系数及吸收系数测量结果与其他研究小组得到的测量结果对比,偏差小于3.4％.
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