【摘 要】
：
Despite progress and continued efforts to control metastatic breast cancer, no effective treatment exists for patients with malignant cells resistant to che
【机 构】
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The International Center for Cell Therapy & Cancer Immunotherapy (CTCI) Tel Aviv Medical Center & To
【出 处】
：
(BITs 3rd Annual World Cancer Congress-2010, Breast Cancer C
论文部分内容阅读
Despite progress and continued efforts to control metastatic breast cancer, no effective treatment exists for patients with malignant cells resistant to chemotherapy, certainly not against the rare cancer initiating cells-cancer stem cellsthat are characteristically primary resistant to chemotherapy.Alloreactive donor lymphocytes were previously shown to eliminate all malignant cells and result in cure [some>25 years and many>10 years disease-free survival] of otherwise incurable patients with a large variety of hematological malignancies fully resistant to maximally tolerated does of chemoradiotherapy followed by rescue with autologous or even allogeneic stem cell transplantation.
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