pH and reduction sensitive mesoporous silica nanoparticles for targeted drug delivery

来源 :Fourth Symposium on Innovative Polymers for Controlled Deliv | 被引量 : 0次 | 上传用户：ppt1000

【摘要】

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【作者】

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Liang Chen Wei Nie Weizhong Wang Haibo Du Ling Tao Dinghua Liu Chuanglong He

【机构】

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College of Chemistry,Chemical Engineering and Biotechnology,Donghua University,Shanghai 201620,China

【出处】

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Fourth Symposium on Innovative Polymers for Controlled Deliv

【发表日期】

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2016年11期

【关键词】

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mesoporous silica nanoparticles pH-responsive reduction responsive drug delivery

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　　Mesoporous silica nanoparticles (MSN) have been intensively studied for drug delivery owing to their outstanding physicochemical properties.Specifically,the rational design of targeted and intelligent responsive MSN is highly desirable to improve the therapeutic efficacy and minimize the side effect of nanocarriers.In our previous work,a pH-responsive MSN drug delivery system was developed.The polyelectrolyte modified MSN exhibited improved biocompatibility and pH-controlled drug release behavior compared to the bare MSN[1].

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pH and reduction sensitive mesoporous silica nanoparticles for targeted drug delivery

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