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The purpose of this study was to compare a dualfreeze protocol with a triple-freeze protocol for hepatic cryoablation in a porcine model.Eighteen cryoablations were performed over an exposed operation field in nine normal porcine livers, using dual-(10-5-10-5) and triple-freeze (5-5-5-5-10-5) protocols.Changes in the temperature of the cryoprobes and the diameter of the iceballs were recorded during the ablation, and pathological changes in the cryozones (zones of tissue destruction) were assessed seven days after the procedure.