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Nowadays, controlled drug delivery technology represents one of the frontier areas of modem medicine and pharmaceutics due to their great capability to regulate drug release to improve therapeutic efficacy and reduce side effects.A big challenge of engineering drug delivery systems is the controlled assembly of purposefully designed molecules, or ensembles of molecules, into nanoscaled structures to provide increasingly precise control at molecular levels, over the structure, properties and function.Despite numerous drug carriers have been developed and tested over the past decades, clinical success is still relatively rare.