Theoretical Insights into Polymorphic Co-crystal of 5-Fluorouracil and 4-Hydroxybenzoic acid:Stabili

来源 :中国化学会第14 届全国计算(机)化学学术会议暨分子模拟国际论坛 | 被引量 : 0次 | 上传用户：jiandancaozuo

【摘要】

：

5-Fluorouracil(5-Fu)is used as active pharmaceutical ingredients in treatment cancer,with moderate aqueous solubility and low permeability.

【作者】

：

Wei Gao Xia-Lin Dai Jia-Mei Chen

【机构】

：

School of Pharmacy,Guangdong Pharmaceutical University,Guangzhou,China,510006

【出处】

：

中国化学会第14 届全国计算(机)化学学术会议暨分子模拟国际论坛

【发表日期】

：

2017年10期

【关键词】

：

polymorphic co-crystal Stability and Solubility 5-Fluorouracil and 4-Hydroxybenz

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　　5-Fluorouracil(5-Fu)is used as active pharmaceutical ingredients in treatment cancer,with moderate aqueous solubility and low permeability.

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Theoretical Insights into Polymorphic Co-crystal of 5-Fluorouracil and 4-Hydroxybenzoic acid:Stabili

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