Exogenous Taurine attenuates mitochondrial oxidative stress and endoplasmic reticulum stress in rat

来源 :中国细胞生物学学会2013年全国学术大会 | 被引量 : 0次 | 上传用户：nizhongyu

【摘要】

：

【作者】

：

杨宇杰刘雯左伋

【机构】

：

复旦大学,基础医学院,细胞与遗传医学系,上海,200032

【出处】

：

中国细胞生物学学会2013年全国学术大会

【发表日期】

：

2013年12期

【关键词】

：

Taurine Taurine Transporter Glucose Deprivation Mitochondrial Oxidative Stress E

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Taurine,a conditional essential amino acid,plays a critical role in cardiovascular functions.Here we examined the effects of taurine on mitochondria and Endoplasmic Reticulum in rat cardiomyocytes during glucose deprivation (GD).Data showed that cell viability,intracellular taurine contents and taurine tranporter expression were decreased during GD.

其他文献

INMAP Affacts Tumorigenesis Dependently on Its Dosage in Cells

Tumorigenesis relies on the change of protein structure,modification and dosage.Modest protein dosage is indispensable for cellular growth and heredity.On the contrary some protein dosage rising drama

会议

INMAPtumorigenesiscell growthcell cycle

DNA polymerase iota is regulated by DNA damage checkpoint controlled JNK/c-Jun signaling and associa

Human DNA polymerase iota (polι) possesses error-prone DNA replication features and performs translesion DNA synthesis.It may be specialized and highly regulated in normalmammalian cells;dysregulation

会议

bladder cancer/DNApolymerase iota/JNKsignaling/mutagenesis/UVdamage

HOXC8 Functions as a Transcription factor to Regulate Cadherin 11 Transcription in Breast Cancer Cel

HOXC8 belongs to homeobox (HOX) family which comprises 39 members in mammalian species.It has been reported that HOXC8 expression is deregulated in several cancers and its expression is apparently upr

会议

HOXC8cadherin 11Transcription

Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation rati

As a well-known phenomenon,total mRNAs poorly correlate to proteins in their abundances as reported.Recent findings calculated with bivariate models suggested even poorer such correlation,while focusi

会议

Translating mRNAProtein abundanceMultivariate correlationTranslation ratioPh

Nkx2-2蛋白非经典入核途径的研究

细胞内,大分子化合物的核质穿梭是一个信号依赖的主动运输过程,分为经典入核途径与非经典入核途径两种,主要由核质转运受体家族负责介导.同源异型蛋白Nkx2-2是胚胎脑与胰腺正常发育过程中必需的转录调节因子.

会议

Nkx2-2同源异性结构域核质转运受体核定位信号

Proteomic studies to identify signaling mechanisms in ovarian cancer

Somatic mutation and altered protein expression patterns cause inappropriate activation and deactivation of key players in cellular signaling,resulting in oncogenic phenotypes.

会议

Ovarian cancertumorigenesissignalingproteomicsposttranslational modification

Rotenone inhibits mTOR signaling by induction of reactive oxygen species leading to apoptosis of neu

Rotenone,an inhibitor of the mitochondrial electron transport chain complex,may induce neuronal apoptosis contributing to neurodegenerative diseases.

会议

RotenonemTORROSApoptosisNeuronal cell

Novel mechanisms of bitter tastant inducing mouse airway smooth muscle cell contraction and relaxati

The bitter tastant chloroquine activates bitter taste receptors (TAS2Rs) and signaling through G protein subtype Gβγ to increase intracellular Ca2+ in airway muscle cells,and this Ca2+ increase result

会议

tas2rbitter tastantairway musclenon-selection cation channelsairway hyperres

miR-449通过调控DNA损伤应答基因XPC影响膀胱尿路上皮癌疾病进展

膀胱癌是我国泌尿生殖系统最常见的肿瘤,其发病率和死亡率均居泌尿肿瘤首位.膀胱癌的演进是多阶段多基因参与的结果,其中DNA损伤应答过程的异常可通过影响细胞周期、凋亡和DNA修复等重要生命活动导致肿瘤基因组的高度不稳定,与肿瘤的发生、发展密切相关.

会议

膀胱尿路上皮癌miR-449XPC

GAS2维持慢性粒细胞白血病细胞生长的功能研究

慢性粒细胞白血病(CML)是正常造血干细胞获得性形成BCR-ABL融合基因而诱发的克隆性血液肿瘤.抑制BCR-ABL酪氨酸激酶的小分子化合物,如Imatinib mesylate能使慢性期患者得到有效缓解,但单一药物尚不能治愈该疾病;这表明深入研究CML致病分子机制、寻找新的治疗靶标仍是CML研究的重点.

会议

CMLcalpainbeta-cateninGAS2HNRPDL

Exogenous Taurine attenuates mitochondrial oxidative stress and endoplasmic reticulum stress in rat

其他学术论文