An Injectable Thermogel with High Radiopacity

来源 :第13届国际聚合物先进技术会议 | 被引量 : 0次 | 上传用户:yan1982zi
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  Thermogelling polymers based on poly(ethylene glycol)(PEG)and biodegradable polyesters,such as poly(lactic acid-co-glycolic acid)(PLGA),poly(lactic acid)(PLA),poly(caprolactone)(PCL)and poly(caprolactone-co-glycolic acid)(PCGA),have been suggested as very promising biomaterials for sustained drug delivery,injectable tissue engineering,prevention of post-surgical adhesion,and so on.In this study,an injectable PEG/polyester thermogel with strong X-ray opacity was designed and synthesized through the conjugation of 2,3,5-triiodobenzoic acid into the hydrophobic end of mPEG-PLA diblock copolymer for the first time.
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