Biophysical and biochemical insight into WHAMM-mediated cytoskeletal coordination and membrane bindi

来源 :第四届全国冷冻电子显微学与结构生物学专题研讨会 | 被引量 : 0次 | 上传用户:commander_ocean
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The microtubule(MT) and actin cytoskeletons organize the mammalian cell cytoplasm and have well-established roles in many dynamic processes,including cell division,migration and membrane trafficking.Here,we focus on WHAMM,a Golgi-associated protein that utilizes MT binding and actin nucleation activities to promote membrane tubulation during intracellular transport.
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