Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia inducible fa

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户：A75395100

【摘要】

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【作者】

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Haiwen Huang Mingzhong Rui Tianwen Fu Depei Wu

【机构】

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The First Affiliated Hospital of Soochow University,Jiangsu Institute of Hematology

【出处】

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The 35th World Congress of the International Society of Hema

【发表日期】

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2014年5期

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Objective s Bone marrow angiogenesis exhibits an important role in multiple myeloma(MM),and angiogenesis often correlates with the prognosis and disease burden of MM.Our previous studies have demonstrated that RGZ can induce growth inhibition in MM cells.Our previous studies have also confirmed that RGZ can inhibit the growth of myeloma xenograft in nude mice.However,the inhibition of angiopoiesis by RGZ in MM has not yet been reported.

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Rosiglitazone suppresses angiogenesis in multiple myeloma via downregulation of hypoxia inducible fa

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