The roles of R2-carboxylate substitutent in determining binding affinity and interaction mode of tri

来源 :全国药物化学学术会议暨第四届中英药物化学学术会议 | 被引量 : 0次 | 上传用户：ufo747

【摘要】

：

Protein kinase CK2 is involved in a variety of important cellular physiological processes and aberrant CK2 activity is associated with a wide variety of human diseases [1].

【作者】

：

Yue Zhou Na Zhang Rugang Zhong

【机构】

：

College of Life Science and Bioengineering,Beijing University of Technology,Beijing 100124,China

【出处】

：

全国药物化学学术会议暨第四届中英药物化学学术会议

【发表日期】

：

2013年11期

【关键词】

：

Tricyclic quinoline analogs Protein kinase 2 Binding affinity Electrostatic inte

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　　Protein kinase CK2 is involved in a variety of important cellular physiological processes and aberrant CK2 activity is associated with a wide variety of human diseases [1].

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