Nitrogen-containing heterocyclic compounds have received much attention as shown by the numerous studies published on their applicability in different areas,especially as drugs1.
The pyrazolidine-3,5-diones,as an important heterocyclic compounds,have represent excellent biological activities such as anti-tumor[1],ant-cardiovascular,antibacterial,antiviral activities.
pyrimidine,benzimidazole and triazole are important classes of heterocyclic compounds that exhibit a broad spectrum of biological activities such as anticancer,antiviral,antibacterial,antioxidant,anxi
Fueled by the spread of multidrug-resistant(MDR)strains and synergy with the HIV pandemic,tuberculosis(TB)remains to be one of the leading causes of death worldwide,especially in China,India,Africa an
The rapid increase of health-threatening infections by Gram-negative pathogens along with the emergence of multidrug-resistant bacterial strains demands the development of novel antibiotics directed a