Prediction of Estrogen Receptor Subtype-Selective Ligands Using Three-Dimensional Biologically Relev

来源 :第十三届全国计算机化学学会会议 | 被引量 : 0次 | 上传用户：hudan913000

【摘要】

：

　　Estrogen receptor(ER)belongs to the nuclear receptor family of ligand modulated transcriptional factors,which has two subtypes,ERα and ERβ.The functions a

【作者】

：

Zheng-Kun Kuang Ben Hu Shi-Yu Feng De-Xin Kong

【机构】

：

StateKeyLaboratoryofAgriculturalMicrobiology,Collegeofinformatics,HuazhongAgriculturalUniversity,Wuh

【出处】

：

第十三届全国计算机化学学会会议

【发表日期】

：

2015年11期

【关键词】

：

Estrogen receptor selectivity BRS-3D support vector machine

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　　Estrogen receptor(ER)belongs to the nuclear receptor family of ligand modulated transcriptional factors,which has two subtypes,ERα and ERβ.The functions and distributions in tissues of the two ER subtypes are different from each other.Over the past years,development of selective estrogen receptor ligands has been of great concern.

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Prediction of Estrogen Receptor Subtype-Selective Ligands Using Three-Dimensional Biologically Relev

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