In silico Prediction of Influenza Neuraminidase Inhibitor using Machine Learning Approaches

来源 :第十三届全国计算机化学学会会议 | 被引量 : 0次 | 上传用户：yin_guohan163

【摘要】

：

　　Recent outbreaks of highly pathogenic and occasional drug-resistant influenza strains have highlighted the need to develop novel anti-influenza therapeutics

【作者】

：

Li Zhang Haixin Ai Hongsheng Liu

【机构】

：

SchoolofLifeScience,LiaoningUniversity,Shenyang110036,ChinaSchoolofLifeScience,LiaoningUniversity,Sh

【出处】

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第十三届全国计算机化学学会会议

【发表日期】

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2015年11期

【关键词】

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Influenza Neuraminidase Inhibitor Machine Learning Methods Random Forest

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　　Recent outbreaks of highly pathogenic and occasional drug-resistant influenza strains have highlighted the need to develop novel anti-influenza therapeutics.Various inhibitors have been developed for neuraminidase but resistance against these drugs in many viral strains makes it an advantageous and interesting task to discover compounds which can be more promising in preventing viral infection through neuraminidase.

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In silico Prediction of Influenza Neuraminidase Inhibitor using Machine Learning Approaches

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