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Frailt y is a state of health signified by an increased vulnerability to adverse health outcomes in the face of stressors.There has been emerging interest on the research of frailty, which focuses on the dynamic interactions within and across the complex adaptive systems underlying the frailty syndrome.The theoretical literature on frailty hypothesizes that frail older adults are characterized by a loss of resilience in the face of stressors, and that the frail and non-frail would differ in terms of the dynamics of physiological systems in response to stimuli.