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  5. Transforming growth factor β-activated kinase 1 inhibits HBV replication and gene expression through

Transforming growth factor β-activated kinase 1 inhibits HBV replication and gene expression through

来源 :2014年APASL专题会议暨第四届乙型病毒性肝炎专题会议 | 被引量 : 0次 | 上传用户：fashion_darling
【摘 要】
：
Background:Transforming growth factor β-activated kinase 1(TAK1) is a key mediator of innate immunity and proinflammatory signaling pathway.Previously,we found that TAK1 was involved in anti-HBV effec
【作 者】
：
Jinke Pang Geng Zhang Libo Tang Mengji Lu Haitao Guo Jian Sun Jinlin Hou Xiaoyong Zhang 
【机 构】
：
State Key Laboratory of Organ Failure Research Gu
【出 处】
：
2014年APASL专题会议暨第四届乙型病毒性肝炎专题会议
【发表日期】
：
2014年4期
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Background:Transforming growth factor β-activated kinase 1(TAK1) is a key mediator of innate immunity and proinflammatory signaling pathway.Previously,we found that TAK1 was involved in anti-HBV effect of toll-like receptor 2 agonist in hepatoma cells(Zhang XY,et al,J Hepatol,2012).Here,we further investigated the function of TAK1 in hepatitis B virus(HBV) replication and gene expression in cell culture and mouse models.
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