OLIGONUCLEOTIDE相关论文
Phosphorothioate oligonucleotide inhibits tissue factor expression in endothelial cells induced by b
Objective: To determine the effect of antiparallel phosphorothioate triplex-forming oligonucleotide (apsTFO),which was d......
Combined transfection of Bcl-2 siRNA and miR-15a oligonucleotides enhanced methotrexate-induced apop
Objective: B-cell lymphoma 2 (Bcl-2) is an important member of the Bcl-2 family of proteins that regulate the induction ......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 探讨生存素(Survivin)反义寡核苷酸(ASODN)诱导人胃癌细胞SGC7901凋亡的作用.方法 设计合成特异性靶向Survivin的ASODN,将胃......
Recently,we reported that deoxyribo-oligonucleotides could induce single chained cationic surfactant aggregation to form......
人类基因组学研究已实现从结构基因组向后基因组的全面转变,现阶段致病基因的克隆实质上已不是传统意义上的基因克隆,而主要是致病......
Summary: Silencing ATM gene gave rise to enhanced apoptotic response to irradiation and irradiation-like chemotherapy ag......
目的初步研究限制性显示技术(RD-PCR)作为一种高密度长链寡核苷酸芯片样本标记方法对芯片杂交信号的影响.方法收集3个健康人外周血......
目的 探讨C-myc反义寡核苷酸(ASODN)对人胆管癌QBC939细胞增殖和侵袭力的影响.方法 合成C-mycASODN,并将其转染QBC939细胞;四甲基......
应用特殊设计的寡核苷酸链纠正点突变技术是20世纪90年代发展起来的一项新技术,在酵母菌、植物细胞、哺乳动物细胞等不同的生物材......
Objective: The aim of the research was to study whether microRNA-15a (miR-15a) oligonucleotide could inhibitcell growth ......
目的 探讨雾化吸入信号转导和转录活化因子1(STAT1)反义寡核苷酸(ASON)干预肺纤维化的最佳给药时机.方法 Wistar雌性大鼠25只随机......
Telomeres are protein-DNA complexes at the terminals of linear chromosomes, which protect chromosomal integrity and main......
DNA microarrays have been acknowledged to represent a promising approach for the detection of viral pathogens. However, ......
A novel typography technique was developed to in situ synthesize oligonucleotide arrays on glass slide, which has the ce......
A novel strategy for in situ maskless synthesis of biochips:Self-driving micro-fluid porous type pri
A novel maskless technique, self-driving micro-fluid porous type printing (SMPTP), was reported to in situ synthesize ol......
目的 探讨成年及幼年羊关节软骨对急性机械性损伤在分子水平的反应.方法 建立羊的不同发育阶段关节软骨组织机械性损伤体外模型,运......
