NEURODEGENERATION相关论文
Distinct Rab7-related Endosomal–Autophagic–Lysosomal Dysregulation Observed in Cortex and Hippocampu
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New insights into Wnt signaling alterations in amyotrophic lateral sclerosis: a potential therapeuti
Amyotrophic lateral sclerosis is a fatal neurodegenerative disorder characterized by upper and lower motor neuron degene......
Neuroinflammation and oxidative stress act in concert to promote neurodegeneration in the diabetic r
Diabetes is a lifelong disease characterized by glucose metabolic imbalance, in which low insulin levels or impaired ins......
Worldwide stroke is increasing in parallel with modernization, changes in lifestyle, and the growing elderly population.......
Stem cells in neuroinjury and neurodegenerative disorders：challenges and future neurotherapeutic pro
The prevalence of neurodegenerative diseases and neural injury disorders is increasing world-wide. Research is now focus......
Amyloid precursor-like protein 2 C-terminal fragments upregulateS100A9 gene and protein expression i
The murine microglial cell line BV2 has neuroprotective effects, but is toxic to neurons by secret-ing inlfammatory cyto......
The accumulation of myelin debris may be a major contributor to the inlfammatory response after diffuse axonal injury. I......
Effects of dizocipine maleate on mitochondrial ultramicrostructure in neurons following traumatic br
BACKGROUND: The effects of N-methyl-D-aspartic acid (NMDA) receptor antagonist on neurodegeneration in the immature brai......
Infantile-onset spinal muscular atrophy is the quintessential example of a disorder characterized by a predominantly neu......
Neuroprotective and anti-inflammatory effects of a therapy combining agonists of nicotinic α7 and σ1
To date there is no treatment able to stop or slow down the loss of dopaminergic neurons that characterizes Parkinson’s......
The canonical Wnt/β-catenin signaling pathway has been shown to play a major role during embryonic development and matu......
Efficacy of short-term multidisciplinary intensive rehabilitation in patients with different Parkins
Parkinson’s disease (PD) can be classified into three motor-based subtypes: postural instability/gait difficulty (PIGD)......
背景 术后认知功能障碍(postoperative cognitive dysfunction,POCD)是麻醉手术后常见的神经系统并发症,尤其在老年人多见.脑内铁......
Effects of dizocipine maleate on mitochondrial ultramicrostructure in neurons following traumatic br
BACKGROUND: The effects of N-methyl-D-aspartic acid (NMDA) receptor antagonist on neurodegeneration in the immature brai......
Amyloid precursor-like protein 2 C-terminal fragments upregulateS100A9 gene and protein expression i
The murine microglial cell line BV2 has neuroprotective effects, but is toxic to neurons by secret-ing inlfammatory cyto......
The accumulation of myelin debris may be a major contributor to the inflammatory response after diffuse axonal injury. I......
Type 2 diabetes is a risk factor for Alzheimer’s disease and Parkinson’s disease. Insulin signaling in the brains of p......
烟酰胺腺嘌呤二核苷酸(NAD+)是生物化学反应的重要介质,作为辅酶参与氧化还原反应,也可以作为底物参与分子信号传递.NAD+在细胞内......
Innate Immunity and Neuroinflammation in the CNS: The Role of Microglia in Toll-Like Receptor-Mediat
小胶质细胞是中枢神经系统内的内源性免疫细胞,在中枢神经系统的固有免疫反应中扮演关键的角色,其主要作用是早期控制感染及激活适......
The VCP-Ufd1-Npl4 complex regulates proteasomal processing within cells by delivering ubiquitinated proteins to the prot......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Aluminium-induced acute neurotoxicity in rats:Treatment with aqueous extract of Arthrophytum (Hammad
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Regional gray matter atrophy and neuropsychologcal problems in relapsing-remitting multiple sclerosi
In multiple sclerosis, gray matter atrophy is extensive, and cognitive deficits and mood disorders are frequently encoun......
Characterization of hippocampal Cajal-Retzius cells during development in a mouse model of Alzheimer
Cajal-Retzius cells are reelin-secreting neurons in the marginal zone of the neocortex and hip-pocampus. The aim of this......
In this study, we established cell models for Parkinson’s disease using rotenone. An RNA interfer-ence vector targeting......
Effects of naringin, a lfavanone glycoside in grapefruits and citrus fruits, on the nigrostriatal do
Recently, we have demonstrated the ability of naringin, a well-known flavanone glycoside of grapefruits and citrus fruit......
Treating Alzheimer’s disease withYizhijiannao granules by regulating expression of multiple proteins
Yizhijiannao granules have been shown to improve cognitive function in Alzheimer’s disease patients. The present study ......
