Primary hepatocytes(PHCs)are widely used in various fields,but the progressive deterioration of liver-specific features ......

Objective: To observe the effect of Qishen decoction on dedifferentiation and autophagy of liver sinusoid endothelial ce......

Objective Chronic atrial fibrillation (AF) results in dedifferentiation of atrial cardiomyocytes that plays an important......

目的通过Oct4介导小鼠肝细胞去分化为Sox17阳性细胞,探索肝胰重编程新途径。方法构建慢病毒载体pWPT-Oct4,包装和浓缩病毒;改良两......

目的 分离培养去分化来源的表皮十细胞(dedifferentiation-derived epidermal stem cells,DDESCs),并进一步观察其表型特征.方法 ......

因创伤、肿瘤切除及先天畸形导致的组织器官缺损,一直是困扰临床医生的棘手难题.目前临床上常用的组织器官重建与修复方法不外乎组......

β细胞的功能缺陷是我国2型糖尿病的主要的发病机制之一。近年来大量研究表明β细胞去分化是β细胞功能缺陷的主要原因,而FOXO1是......