BIOEQUIVALENCE相关论文
Relative Bioavailability of Rifampicin in Four Chinese Fixed-dose Combinations Compared with Rifampi
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在生物等效性(BE)研究中,因多种原因,会经常遇到重复BE研究的问题.对这类情况如何进行BE统计分析,目前并没有指导原则可以参考.本......
目的:研究在空腹和餐后条件下国产左乙拉西坦片的生物等效性,并探讨餐后给药试验的意义和样本量对试验结果的影响。方法:分别进行......
目的研究2种西酞普兰在健康受试者体内的生物等效性。方法 18例健康男性受试者随机分组,自身对照,单次口服西酞普兰片20 mg,测定西......
Relative Bioavailability of Rifampicin in Four Chinese Fixed-dose Combinations Compared with Rifampi
Background:Decreases in the bioavailability of rifampicin (RFP) can lead to the development of drug resistance and treat......
本文通过对荣华二采区10...
Power Analysis and Sample Size Determination for Crossover Trials with Application to Bioequivalence
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
Objective To evaluate the bioequivalence between recombinant human growth hormone ( rhGH) for reconstitution, and two do......
探讨多变量多水平模型在生物等效性评价中的应用价值.以4×4交叉试验设计的国产和进口罗格列酮药物生物等效性评价为研究实例,研究......
目的 在中国健康男性志愿者中对国产阿托伐他汀(商品名:阿乐)与进口阿托伐他汀(商品名:立普妥)进行单次空腹给药的药代动力学和生......
A rapid and sensitive liquid chromatography-tandem mass spectrometry method(LC-MS/MS) was developed and validated for th......
目的：研究中国健康受试者单次口服盐酸阿夫唑嗪分散片和片剂的药代动力学行为并评价2种药物间的生物等效性。方法随机交叉，单次试验......
目的评价国产阿奇霉素肠溶胶囊与进口阿奇霉素片剂的质量一致性。方法双周期、随机交叉试验设计,24名健康男性受试者单次口服阿奇......
研究茶碱缓释干混悬剂(受试制剂)和茶碱缓释片(参比制剂)在Beagle犬体内的药动学和生物等效性。进行双周期交叉试验,每条Beagle犬......
LC-MS/MS Method for Determination of Megestrol in Human Plasma and Its Application in Bioequivalence
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Quantification of desloratadine in human plasma by LC-ESI-MS/MS and application to a pharmacokinetic
A simple,sensitive,and specific liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for the q......
