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目的:探讨多烯磷脂酰胆碱治疗酒精性脂肪肝(AF)的疗效。方法:将60例AF患者随机分为治疗组和对照组各30例,治疗组用多烯磷脂酰胆碱、对照组应用甘利欣进行疗效对比。结果:治疗组30例中治愈18例,显效5例,有效5例,无效2例,总有效率为93.3%;对照组30例中治愈10例,显效4例,有效5例,无效11例,总有效率为63.3%。治疗组与对照组疗效比较差异有统计学意义(P<0.01)。结论:在戒酒的基础上采用多烯磷脂酰胆碱治疗可以尽快改善患者症状和体征,改善肝功能,且具有良好的安全性。多烯磷脂酰胆碱是治疗酒精性脂肪肝的理想药物。
Objective: To investigate the therapeutic effect of polyene phosphatidylcholine on alcoholic fatty liver disease (AF). Methods: Sixty patients with AF were randomly divided into treatment group and control group, 30 cases each. The treatment group was treated with polyene phosphatidylcholine, while the control group was treated with salvia miltiorrhiza for comparison. Results: In the treatment group, 18 cases were cured in 30 cases, 5 cases were markedly effective, 5 cases were effective, 2 cases were ineffective and the total effective rate was 93.3%. In the control group, 10 cases were cured, 4 cases markedly effective, 5 effective and 11 ineffective , The total effective rate was 63.3%. There was significant difference between the treatment group and the control group (P <0.01). Conclusion: The treatment of polyene phosphatidylcholine on the basis of abstinence can improve the symptoms and signs of patients and improve the liver function as soon as possible, and has good safety. Polyene phosphatidylcholine is the ideal drug for the treatment of alcoholic fatty liver.