论文部分内容阅读
我院自1997年12月～1998年12月应用米非司酮配伍米索前列醇终止宫内孕12周～16周妊娠,获得满意效果;同时,与利凡诺引产相比较,有较好的临床疗效。现报道如下。 1 资料与方法 选择中期妊娠12周～16周要求终止妊娠者共100例,年龄20～40岁,无使用米非司酮及米索前列醇、利凡诺禁忌症。观察组为A组,用药方法:口服米非司酮200mg(上海华联制药厂生产25mg/片),36小时后阴道后穹窿放置米索前列醇600μg(澳大利亚Searle厂生产200μg/片),口服米非司酮前后2小时需空服。对照组为B组,在B超定位后经腹壁羊膜腔内注射利凡诺50～100mg。A与B组各50例。 观察完全流产率、不完全流产率、胎儿娩出时间、术后发热率。 评判标准为:完全流产为用药后36小时胎儿胎盘自然娩出不需要清宫者,不完全流产为用药后阴道出血多或胎盘剥离不全需钳刮或清宫术者,引产失败归为不完全流产之列;胎儿排出时间为用药后至胎儿娩出时间。
Our hospital from December 1997 to December 1998 application of mifepristone with misoprostol termination of intrauterine pregnancy for 12 weeks to 16 weeks of pregnancy, with satisfactory results; the same time, compared with rivanol induction of labor is better The clinical efficacy. Report as follows now. 1 Materials and Methods Selection of mid-pregnancy 12 weeks to 16 weeks require termination of pregnancy a total of 100 cases, aged 20 to 40 years old, without the use of mifepristone and misoprostol, rivanol contraindications. The observation group was Group A, and the drug was administered orally. Mifepristone 200mg (Shanghai Hualian Pharmaceutical Factory produced 25mg / tablet) 36 hours later, vaginal fornix placed misoprostol 600μg (Australia Searle plant production 200μg / tablet), oral Mifepristone 2 hours before and after emptying. The control group was Group B, and 50-100 mg of rivanol was injected into the amniotic cavity after abdominal ultrasound. A and B group of 50 cases. To observe the complete abortion rate, incomplete abortion rate, fetal delivery time, postoperative fever rate. Criteria for evaluation: complete abortion 36 hours after treatment of fetal placenta naturally do not need to clear those who are not, incomplete abortion for vaginal bleeding after medication or placental detachment required forceps curettage or curettage, induction of abortion as incomplete abortion ; Fetal discharge time after delivery to the fetus.