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目的探讨巨细胞病毒（ＣＭＶ）感染与慢性肾盂肾炎发病的关系。方法应用免疫斑点法检测慢性肾盂肾炎患者尿液中ＣＭＶ，酶联免疫吸附试验检测患者血清中ＣＭＶ抗体。结果６８例慢性肾盂肾炎患者中３６例尿液ＣＭＶ抗原检测阳性（５３％），３９例血清ＣＭＶ抗体阳性（５７％）；５０名健康对照组尿液ＣＭＶ抗原阳性４例（８％），血清ＣＭＶ抗体阳性７例（１４％），二组相比较，差异有非常显著意义（Ｐ＜０．０１）。结论提示ＣＭＶ感染可能是肾盂肾炎病因中的一个重要因素
Objective To investigate the relationship between cytomegalovirus (CMV) infection and chronic pyelonephritis. Methods The CMV in urine of patients with chronic pyelonephritis was detected by immunofluorescence method. CMV antibody was detected by enzyme-linked immunosorbent assay. Results The urine CMV antigen was positive in 36 cases (53%) and CMV antibody in 39 cases (57%) in 68 cases of chronic pyelonephritis. The urine samples were positive in 4 cases (8%) of CMV antigen in 50 healthy controls, CMV antibody positive in 7 cases (14%), compared with the two groups, the difference was significant (P <0.01). Conclusions suggest that CMV infection may be an important cause of pyelonephritis