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报道162例小儿活动性人巨细胞病毒感染的临床研究。所有病例CMV-IgM抗体皆阳性。48/71例尿中找到巨细胞包涵体。先天性感染组79例,其中全身性感染32例。年龄3周~12周组29例。该两组临床表现以病理性黄疸、肝脾肿大和肝损害为主,余为先天畸形和神经系统异常(17/31例有听通路传导障碍)。先天组中新生儿窒息20例。>12周龄组54例,其中肾病、肾炎或不明原因的血尿、蛋白尿共32例。死亡4例。借此以加深对该病的认识
A report of 162 cases of pediatric active human cytomegalovirus infection in clinical research. CMV-IgM antibodies were positive in all cases. 48/71 cases of urine found in giant cell inclusion bodies. 79 cases of congenital infection, including 32 cases of systemic infection. 29 cases were aged from 3 weeks to 12 weeks. The two groups of clinical manifestations of pathological jaundice, hepatosplenomegaly and liver damage-based, more than congenital malformations and nervous system abnormalities (17/31 cases of hearing pathway conduction disorder). Inborn group of 20 cases of neonatal asphyxia. > 12 weeks old group of 54 cases, including nephropathy, nephritis or unexplained hematuria, proteinuria in 32 cases. 4 died. In order to deepen the understanding of the disease