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Vi抗原是伤寒杆菌、丙型副伤寒杆菌和枸橼酸菌属某些血清型的表面抗原.自从1934年Felix首先发现Vi抗原以来,迄今做了大量的研究工作,现将有关资料综述如下.Vi抗原的理化及生物学性质Vi抗原是一种高度聚合的酸性多糖,由N-乙酰-氨己糖醛酸组成,分子量为10~6左右.用超声波处理弗劳地枸橼酸杆菌Vi抗原后,其比粘和相对粘滞度均降低.经处理的Vi抗原糖苷键断裂,发生部分解聚,分子量从10~6降到10~4.用温和的酸碱处理Vi抗原,
The Vi antigen is a surface antigen of some serotypes of Salmonella typhi, Paratyphoid Salmonella and Citrobacter genus, and since the first discovery of Vi antigen by Felix in 1934, a great deal of research has been done to date, and the relevant information is summarized as follows. Vi antigens physicochemical and biological properties Vi antigen is a highly polymeric acidic polysaccharides, composed of N-acetyl-aminohexyluronic acid molecular weight of about 10 to 6. Ultrasonic treatment of Citrobacter freundii Vi antigen After the treatment, the Vi antigen glycosidic bond rupture, partial depolymerization, the molecular weight decreased from 10 to 6 to 10 to 4. With a mild acid-base treatment of Vi antigen,