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目的探讨快速减压对兔动脉血气、电解质和肺病理改变的影响。方法将14只实验兔放入加压舱中,于5min内用压缩空气加压至0.6MPa,停留60min,然后于3~5min内减至常压。分别于进舱前、出舱后3h和3d,进行动脉血气、电解质和肺病理检查。结果(1)快速减压可造成兔动脉血氧分压(PaO2)、氧饱和度(SaO2)和二氧化碳分压(PaCO2)下降;红细胞压积(Hct)升高。(2)快速减压可造成兔肺泡壁充血、肺泡腔内渗出,肺毛细血管内气泡形成。结论(1)快速减压可造成家兔动脉血气改变和血液浓缩。(2)肺毛细血管内气泡可能是引起动脉血气改变和血液浓缩的原因。
Objective To investigate the effects of rapid decompression on arterial blood gases, electrolytes and pulmonary pathology in rabbits. Methods 14 experimental rabbits were placed in a pressurized chamber and pressurized with compressed air to 0.6 MPa within 5 min. The suspension was maintained for 60 min and then reduced to normal pressure within 3 to 5 min. Before entering the cabin, 3h and 3d after the exit, arterial blood gases, electrolytes and lung pathology were examined. Results (1) Rapid decompression can lead to decreased arterial oxygenation (PaO2), oxygen saturation (SaO2), and partial pressure of carbon dioxide (PaCO2) in rabbits; hematocrit (Hct) increased. (2) Rapid decompression can cause rabbit alveolar wall congestion, alveolar exudate, the formation of air bubbles in the pulmonary capillaries. Conclusions (1) Rapid decompression can cause arterial blood gas changes and blood concentration in rabbits. (2) Bubbles in the pulmonary capillaries may be the cause of arterial blood gas changes and blood concentration.