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目的研究高压氧(Hyperbaric Oxygen,HBO)治疗对小儿重度脑外伤昏迷患者的影响。方法患者随机分为HBO治疗组38例和对照组35例,治疗组采用常规治疗加高压氧综合治疗,对照组采用常规治疗,比较两组的治疗效果。结果HBO治疗组和对照组总有效率分别为94.7%和82.9%,HBO治疗组优于对照组,差异有统计学意义(P<0.05)。结论高压氧通过增加大脑的血氧含量、收缩脑血管减轻脑水肿、增加椎动脉供血等来保护神经细胞,促进患者苏醒,改善患者的神经功能,HBO综合治疗小儿重型颅脑外伤疗效显著。
Objective To investigate the effect of Hyperbaric Oxygen (HBO) on coma patients with severe traumatic brain injury in children. Methods The patients were randomly divided into HBO treatment group (38 cases) and control group (35 cases). The treatment group was treated with conventional therapy combined with hyperbaric oxygen therapy, while the control group was treated with conventional therapy. The therapeutic effect was compared between the two groups. Results The total effective rate of HBO treatment group and control group was 94.7% and 82.9%, respectively, HBO treatment group was superior to the control group, the difference was statistically significant (P <0.05). Conclusion Hyperbaric oxygen can protect neurons by increasing cerebral blood oxygen content, cerebral vasoconstriction cerebral edema, increasing blood supply of vertebral artery, promoting patients’ recovery and improving neurological function. HBO treatment of children with severe craniocerebral trauma has a significant effect.