Cp_2ZrCl_2-catalyzed synthesis of 2-aminovinyl benzimidazoles under microwave conditions

• 作 者: Qi Sun Cheng-Jun Wang Shan-Shan Gong Yong-Jian Ai Hong-Bin Sun
• 机 构: Jiangxi Key Laboratory of Organic Chemistry,Jiangxi Science and Technology Normal University,Departm
• 出 处: Chinese Chemical Letters
• 发表日期: 2015年03期
• 关键词: microwave catalyzed irradiation equiv heating condensation zirconium moiety spec

A microwave-assisted general method for the synthesis of 2-aminovinyl benzimidazoles has been developed.Treatment of the 1,2-phenylenediamines and N-arylated/N,N-dialkylated 3-aminoacroleins with bis(cyclopentadienyl)zirconium(IV) dichloride(Cp2Zr Cl2) as the catalyst under microwave irradiation for 3–5 min followed by in situ Mn O2 oxidation afforded thirteen 2-aminovinyl benzimidazoles in good yields.

A microwave-assisted general method for the synthesis of 2-aminovinyl benzimidazoles has been developed. Treatment of the 1,2-phenylenediamines and N-arylated / N, N-dialkylated 3-aminoacroleins with bis (cyclopentadienyl) zirconium (IV) dichloride Cp2Zr Cl2) as the catalyst under microwave irradiation for 3-5 min followed by in situ Mn O2 oxidation afforded thirteen 2-aminovinyl benzimidazoles in good yields.