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目的 :探讨绝经后妇女骨密度与血清降钙素及血清骨型碱性磷酸酶的关系 ;方法 :测定 15 0例绝经后妇女的上述 3项指标 ,并以 42例中青年妇女作对照 ;结果 :绝经后妇女骨密度与血清降钙素呈显著正相关关系 (r =0 .413 ,P <0 .0 1) ,而与血清骨型碱性磷酸酶呈显著负相关关系 (r =-0 .5 12 ,P <0 .0 5 ) ,并且绝经后妇女骨密度和血清降钙素显著低于中青年妇女 (P <0 .0 5 ,P <0 .0 1) ,而血清骨型碱性磷酸酶则显著高于中青年妇女 (P <0 .0 5 ) ;结论 :绝经后妇女骨密度和血清降钙素显著降低 ,而血清骨型碱性磷酸酶明显升高 ,易患骨质疏松症 ,应针对病因 ,及早防治
OBJECTIVE: To investigate the relationship between bone mineral density (BMD) and serum calcitonin and serum osteocalcin in postmenopausal women.Methods: The above three indexes of 150 postmenopausal women were measured and compared with 42 young and middle-aged women. Results : There was a significant positive correlation between bone mineral density and serum calcitonin in postmenopausal women (r = 0.41, P <0.01), but negatively correlated with serum bone alkaline phosphatase .5 12, P <0.05), and the bone mineral density and serum calcitonin in postmenopausal women were significantly lower than those in young and middle-aged women (P <0.05, P <0.01) (P <0.05) .Conclusion: Bone mineral density and serum calcitonin in postmenopausal women were significantly lower than those in middle-aged and young women (P <0.05), while serum bone alkaline phosphatase Osteoporosis, should be for the cause, early prevention and treatment