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作者以羟氨喹(Oxamniquine)加Plas-tifix(一种低容量可溶性氯丁橡胶)制成涂肤剂进行了抗血吸虫和预防感染的实验观察,结果如下。抗血吸虫作用:实验动物分为3组,每组小鼠10只,各感染曼氏血吸虫尾蚴100条。于感染后7周,将涂肤剂按450毫克/公斤、225毫克/公斤和112.5毫克/公斤分别涂于小鼠背部,涂药面积为4平方厘米,并在涂药后8天解剖,检查虫体分布和卵谱变化。实
The authors tested anti-schistosomes and infection prevention using Oxamniquine Plus Plas-tifix (a low-volume soluble neoprene) as an antiseptic. Results are as follows. Anti-schistosome effect: experimental animals were divided into 3 groups, 10 mice in each group, each infected with 100 Schistosoma mansoni cercariae. At 7 weeks post-infection, the skin lotion was applied to the back of the mice 450 mg / kg, 225 mg / kg and 112.5 mg / kg, respectively, in an area of 4 cm 2 and dissected 8 days after application Distribution of parasites and changes in egg spectrum. real