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特发性肺纤维化常伴有各种血清学异常,但并发自身免疫性溶血性贫血者罕见。现报道1例肺纤维化合并自身免疫性溶血患者,经用副肾皮质类固醇治疗,两疾患皆得显著改善,现报道于下: 患者,男,72岁,因咳嗽、咯痰,伴有劳动时呼吸困难加重求诊。检查:面色发绀,眼睑结膜贫血、球结膜黄疸,两下肺野可闻特殊罗音(Velero罗音)。血液检查符合自身免疫性贫血。胸片可见双肺下部有弥漫性网状阴影;胸部CT除可见网状阴影外,还可见密集囊泡群;镓闪烁扫描,可见两侧肺下野有镓聚集。病理检查可见肺泡隔壁肥厚及中度淋巴细胞浸润、各处纤维增
Idiopathic pulmonary fibrosis often accompanied by a variety of serological abnormalities, but complicated by autoimmune hemolytic anemia are rare. It is reported in 1 cases of pulmonary fibrosis with autoimmune hemolytic patients, after treatment with para renal corticosteroids, both diseases have been significantly improved, are reported below: patients, male, 72 years old, due to cough, expectoration, accompanied by labor Exacerbation of breathing difficulties when consultation. Check: looking cyanotic, conjunctival anemia, conjunctival jaundice, lung field can be heard twice under the special rales (Velero rales). Blood tests are in line with autoimmune anemia. Chest radiograph shows diffuse reticular shadow in the lower part of the lungs. In addition to the reticular shadow, chest CT showed dense vesicles. Gallium scintigraphy showed gallium accumulation on both sides of the lungs. Pathological examination showed alveolar septal hypertrophy and moderate lymphocytic infiltration, fiber everywhere