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目的分析鼻咽部非霍奇金淋巴瘤的临床特点、治疗方法、疗效及预后。方法分析32例鼻咽部非霍奇金淋巴瘤的临床资料,32例鼻咽部非霍奇金淋巴瘤接受放疗和(或)化疗。结果治疗后CR 18例,PR 10例,PD 4例,有效率(CR+PR)87.5%。第1年死亡8例,T/NK细胞淋巴瘤占62.5%、有B症状占53.1%,3年生存率为71.9%(23/32),5年生存率为59.4%(19/32)。存活5年以上的病例均为无B症状,低、中度恶性及Ⅰ、Ⅱ期病例,B细胞淋巴瘤占37.5%。化疗加局部放疗占78.1%。结论高度恶性、T/NK细胞、有B症状者预后较差,分期越早预后越好,化疗加局部放疗预后较好。
Objective To analyze the clinical features, treatment, efficacy and prognosis of nasopharyngeal non-Hodgkin’s lymphoma. Methods 32 cases of nasopharyngeal non-Hodgkin’s lymphoma were analyzed. 32 cases of nasopharyngeal non-Hodgkin’s lymphoma received radiotherapy and / or chemotherapy. Results After treatment CR 18 cases, PR 10 cases and PD 4 cases, the effective rate (CR + PR) 87.5%. The first year died of 8 cases, T / NK cell lymphoma accounted for 62.5%, B symptoms accounted for 53.1%, 3-year survival rate was 71.9% (23/32), 5-year survival rate was 59.4% (19/32). Survival of more than 5 years in patients with no symptoms of B, low, moderate and Ⅰ, Ⅱ cases, B cell lymphoma accounted for 37.5%. Chemotherapy and radiotherapy accounted for 78.1%. Conclusion The prognosis of patients with highly malignant T / NK cells and B symptoms is poor. The earlier the stage of the prognosis, the better prognosis and the better prognosis of chemotherapy and local radiotherapy.