论文部分内容阅读
目的探讨肺曲霉病的临床特征以及诊断和治疗特点,以提高对该病的认识。方法回顾性分析2009年某院经治的29例肺曲霉病患者的临床资料。结果 29例患者中女11例,男18例,发病年龄14~88岁,28例有基础疾病。多以呼吸道疾病入院,主要临床症状为咳嗽、咳黏痰、咯血或咳血丝痰、胸痛、气短和发热等。两性霉素B联合伊曲康唑治疗,好转及治愈18例,死亡11例。结论曲霉菌病临床表现缺乏特异性,常合并多种基础疾病,肺部是曲霉菌最主要的感染部位,进展迅速,应早诊断、早治疗、提高生存率。
Objective To investigate the clinical features of pulmonary aspergillosis and the characteristics of diagnosis and treatment in order to improve its understanding of the disease. Methods The clinical data of 29 patients with pulmonary aspergillosis who were treated by a hospital in 2009 were retrospectively analyzed. Results Among the 29 patients, 11 were women and 18 were males. The age of onset was from 14 to 88 years old. The 28 patients had underlying diseases. Mostly admitted to respiratory diseases, the main clinical symptoms of cough, cough and phlegm, hemoptysis or cough bloody sputum, chest pain, shortness of breath and fever. Amphotericin B combined with itraconazole treatment, improvement and cure in 18 cases, 11 patients died. Conclusion The clinical manifestations of Aspergillus are lack of specificity, often combined with a variety of underlying diseases. The lungs are the most important infection site of Aspergillus. The progress is rapid and should be diagnosed and treated as early as possible to improve the survival rate.