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小儿全麻术后易发生呕吐而引起生理功能紊乱、延长治疗时间及引起众多并发症。本文的目的是比较术中预防性应用小剂量枢复宁(ondansetron)50μg/kg复合地塞米松150μg/kg与单独大剂量应用枢复宁150μg/kg的抗呕吐效果。选择200例2～14岁年龄阶段的健康小儿,行择期斜视矫正术。术前20～30min口服咪唑安定0.5mg/kg,入室后常规监测血流动力学指标,应用非麻醉剂量N_2O使患儿镇静。用异丙酚2.5～3.5mg/kg,利多卡因0.5mg/kg及氟烷、N_2O麻醉诱导。在适当麻醉深度下行气管插管或用喉罩人工通气,必要时应用美维松0.25mg/kg使肌肉足够松弛。然后将患儿随机双盲分为2组:A组(n=100)静注枢复宁
Pediatric general anesthesia prone to vomiting caused by physiological disorders, prolonged treatment time and cause many complications. The purpose of this article is to compare the prophylactic use of small doses of ondansetron 50μg / kg dexamethasone 150μg / kg and high-dose application of independent high-dose 150mg / kg of anti-vomiting effect. Select 200 cases of 2 to 14 years of age healthy children, elective strabismus surgery. Preoperative 20 ~ 30min oral midazolam 0.5mg / kg, after admission routine monitoring of hemodynamic indicators, the application of non-narcotic doses of N_2O to sedation in children. Propofol 2.5 ~ 3.5mg / kg, lidocaine 0.5mg / kg and halothane, N_2O anesthesia induced. Tracheal intubation or laryngeal mask artificial ventilation at the appropriate depth of anesthesia, if necessary, the application of meclizine 0.25mg / kg enough muscle relaxation. The children were then randomly double-blindly divided into two groups: A group (n = 100) intravenous rehabilitation Ning