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应用高效液相色谱法检测１０例稳定型心绞痛（ＳＡ组）、１２例不稳定型心绞痛（ＵＡ组）、１２例急性心肌梗塞（ＡＭＩ组）患者、４２例正常人（对照组）的尿纤维蛋白肽Ａ（ＦＰＡ）水平，结果分别为：２８．１±１３．３、３９．６±１１．８、８８．２±２８．９、２５．４±１０．３ｎｇ／ｍｇＣｒ．ＡＭＩ组明显高于其它各组（Ｐ＜０．０１）ＵＡ组高于ＳＡ组（Ｐ＜０．０５）、对照组（Ｐ＜０．０１）．ＳＡ组与对照组的尿ＦＰＡ无显著差异．表明冠心病患者体内存在高凝状态．提示，尿ＦＰＡ的定量对冠心病类型的鉴别有一定价值，认为通过动态观察尿ＦＰＡ变化有助于判断病情．
The urinary fibers of 10 patients with stable angina pectoris (SA group), 12 patients with unstable angina pectoris (UA group), 12 patients with acute myocardial infarction (AMI group) and 42 healthy controls (control group) were detected by HPLC. Protein A (FPA) levels, the results were: 28.1 ± 13.3, 39.6 ± 11.8, 88.2 ± 28.9, 25.4 ± 10.3 ng / mgCr, respectively. AMI group was significantly higher than the other groups (P <0.01) UA group was higher than the SA group (P <0.05), the control group (P <0.01). There was no significant difference in urinary FPA between SA group and control group. Show that patients with coronary heart disease hypercoagulable state. Tip, urine FPA quantitative determination of the type of coronary heart disease have some value, that by dynamic observation of urine FPA changes help to determine the condition.