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为了解肌肉活检对单纯性多发性肌炎(SPM)与肢带型肌营养不良(LGMD)的鉴别价值,本文对比分析了37例 SPM 与9例 LGMD 患者的肌肉活检光镜观察结果及临床资料,结果发现两者在肌纤维变性、坏死、萎缩及炎症细胞浸润、间质增生方面有很多相似之处,但亦各有其特殊性,且各种改变间的组合方式在两病中各不相同。若结合临床特点,一般可作出鉴别诊断,故肌活检仍为目前鉴别 SPM与 LGMD 的决定性诊断方法。
In order to understand the differential value of muscle biopsy for simple polymyositis (SPM) and limb muscular dystrophy (LGMD), the results of muscle biopsy and clinical data of 37 patients with SPM and 9 patients with LGMD were analyzed. , The results showed that there are many similarities between the two in muscle fiber degeneration, necrosis, atrophy and inflammatory cell infiltration, interstitial hyperplasia, but also have their own particularities, and a combination of changes between the two diseases vary . If combined with clinical features, the general can make a differential diagnosis, so the muscle biopsy is still the definitive diagnosis of SPM and LGMD diagnostic methods.