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本文以冠状动脉血流量、颈动脉平均血压、心率、心外膜心电图ST段总和(ΣST),以及结扎左冠状动脉前降支(LAD)20h后心肌用硝基四氮唑蓝(N-BT)染色测定心肌梗塞的范围等指标,在心肌梗塞模型狗上观察了静脉注射茜Ⅱ和丹参注射液对实验性心肌梗塞的作用.实验表明,在使血压降低、心率减慢和ΣST减小等方面,两药在各自常用有效量的情况下作用基本相似,但在使冠状动脉流量增加和使心肌梗塞范围缩小等方面,茜Ⅱ的作用却明显地超过丹参注射液(P<0.02).
In this study, coronary artery blood flow, carotid mean blood pressure, heart rate, epicardial electrocardiogram ST-segment summation (ΣST), and ligation of left anterior descending coronary artery (LAD) 20h after myocardial nitroblue tetrazolium blue (N-BT ) Staining to determine the extent of myocardial infarction and other indicators of myocardial infarction model dogs were observed intravenous injection of Sims Ⅱ and Danshen injection on experimental myocardial infarction.Experiments have shown that in lowering blood pressure, heart rate and ΣST decrease In terms of the two drugs in the commonly used effective amount of the role of the case is similar, but in the coronary flow and myocardial infarction to reduce the scope of such aspects, the role of aldrin Ⅱ significantly more than Salvia injection (P <0.02).