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目的:探讨联合应用依达拉奉和血栓通治疗大面积缺血性脑卒中的应用效果及不良反应。方法:按照随机数字表法将2009年12月～2011年12月在我院急诊科就诊的98例大面积缺血性脑卒中患者分为两组,其中一组为对照组,对照组患者在接受吸氧、抗血小板聚集、维持电解质平衡、降血糖以及护胃等支持对症治疗的同时应用依达拉奉进行治疗,另一组为观察组,观察组患者在对照组患者治疗的基础上加用血栓通进行治疗。1个疗程后,比较两组患者的临床疗效和不良反应发生情况。结果:观察组患者的治疗总有效率(53.06%)明显高于对照组的治疗总有效率(24.49%)。结论:联合应用依达拉奉和血栓通治疗大面积缺血性脑卒中可明显改善患者的神经功能缺损程度、减轻患者的残疾程度、提高患者的生活自理能力。
Objective: To investigate the combined effect of Edaravone and Xueshuantong in treating large area ischemic stroke and its adverse reactions. Methods: According to the random number table method, 98 cases of ischemic stroke in our hospital emergency department from December 2009 to December 2011 were divided into two groups. One group was control group, and the other one was control group Accept oxygen, anti-platelet aggregation, maintain electrolyte balance, hypoglycemia and support the symptomatic treatment of symptomatic treatment with edaravone treatment, and the other for the observation group, observation group patients in the control group based on the treatment of patients plus Thrombus for treatment. After a course of treatment, the clinical efficacy and adverse reactions of the two groups were compared. Results: The total effective rate (53.06%) in the observation group was significantly higher than that in the control group (24.49%). Conclusion: The combination of edaravone and Xueshuantong in the treatment of ischemic stroke can significantly improve the degree of neurological deficits, reduce the degree of disability and improve the patients’ self-care ability.