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目的观察阿奇霉素联合红霉素治疗小儿支原体肺炎的临床效果。方法选取医院收治的小儿支原体肺炎患儿120例为研究对象,随机分为观察组和对照组,每组60例。观察组采用红霉素和阿奇霉素联合治疗,对照组采用阿奇霉素治疗。观察比较2组患儿的治疗效果、临床症状消失时间及并发症发生情况。结果观察组总有效率为98.33%,高于对照组的86.67%(P<0.05);观察组退热时间、止咳时间、肺部啰音消失时间均短于对照组(P<0.05);观察组不良反应发生率为10.01%,明显低于对照组的56.66%(P<0.01)。结论阿奇霉素联合红霉素治疗小儿支原体肺炎效果显著,安全性较高,值得临床推广应用。
Objective To observe the clinical effect of azithromycin combined with erythromycin in treating children with mycoplasma pneumonia. Methods A total of 120 children with mycoplasma pneumonia admitted to hospital were selected as study subjects and randomly divided into observation group and control group with 60 cases in each group. The observation group was treated with erythromycin and azithromycin, while the control group was treated with azithromycin. The therapeutic effects, the disappearance of clinical symptoms and the incidence of complications in the two groups were observed and compared. Results The total effective rate in the observation group was 98.33%, which was significantly higher than that in the control group (86.67%, P <0.05). The observation group had shorter antipyretic time, cough-relieving time and pulmonary rales disappearance time (P <0.05) The incidence of adverse reactions was 10.01%, which was significantly lower than that of the control group (56.66%, P <0.01). Conclusion Azithromycin combined with erythromycin in children with mycoplasma pneumonia has a significant effect, high safety, worthy of clinical application.