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目的比较慢性肾功能衰竭患者与普通人群抑郁的发病率。方法选40名慢性肾衰患者,使用汉密顿抑郁量表进行抑郁诊断,40名健康者作为对照组。结果慢性肾衰组抑郁发病率为45%,对照组抑郁发病率为2.5%,两组间抑郁发病率具有统计学差异(P=0.000)。慢性肾衰组轻、中、重度抑郁发病率为20%,10%,15%,对照组轻、中、重度抑郁发病率分别为为2.5%,0%,0%,两组间轻、中、重度抑郁发病率均具有统计学差异(P=0.000,P=0.000,P=0.000)。结论慢性肾功能衰竭患者抑郁发病率显著高于普通人群。认知和治疗慢性肾衰相关抑郁是非常重要的。
Objective To compare the incidence of depression in patients with chronic renal failure and the general population. Methods Forty chronic renal failure patients were selected, depression was diagnosed by Hamilton Depression Scale, and 40 healthy controls were used as control group. Results The incidence of depression was 45% in chronic renal failure group and 2.5% in control group. There was a significant difference in the incidence of depression between the two groups (P = 0.000). The incidence of mild, moderate and severe depression in chronic renal failure group was 20%, 10% and 15% respectively. The incidences of mild, moderate and severe depression in control group were 2.5%, 0% and 0% (P = 0.000, P = 0.000, P = 0.000). Conclusion The incidence of depression in patients with chronic renal failure is significantly higher than that of the general population. Cognition and treatment of chronic kidney failure related depression is very important.