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近年,VEGF-R3、LYVE-1、podoplanin和PROX-1等淋巴管内皮细胞特异性标志物的发现为研究淋巴管的特征与淋巴管形成过程提供了有力的工具,应用这些特异性标志物,多种组织中淋巴管的形态及特征逐渐明了,但是,子宫内膜中淋巴管的分布,各家报道不一,现简要综述淋巴管形成机制的新进展,并且对子宫内膜淋巴管形成的研究做一总结。
In recent years, the discovery of specific markers of lymphatic endothelial cells such as VEGF-R3, LYVE-1, podoplanin and PROX-1 provide a powerful tool for studying the characteristics of lymphatic vessels and lymphangiogenesis. Using these specific markers, However, the distribution of lymphatic vessels in the endometrium varies from one reportage to another. Now we briefly review the new progress of the lymphangiogenesis mechanism, and the regulation of lymphangiogenesis on the endometrium Research to make a summary.