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双相性鳞片状腺泡状肾细胞癌(BSARCC)是最近阐述的一种具有特殊形态学特征的肿瘤。本文使用常规组织学、免疫组化、阵列比较基因组杂交技术(aC GH)及荧光原位杂交技术分析来自12家医院的21例BSARCC。男性11例,女性10例,年龄范围53~79岁;肿瘤直径1.5~16 cm;14例患者获得随访信息(随访1~96个月),5例发现转移性播散。所有肿瘤均由两种细胞群构成,呈器官样结构排列:缺乏胞质的、小的低级别瘤细胞通常衬覆在腺泡状结构的里面,而
Biphasic scaly acinar renal cell carcinoma (BSARCC) is a recently described tumor with a special morphological characteristics. In this study, 21 patients with BSARCC from 12 hospitals were analyzed using routine histology, immunohistochemistry, array-based comparative genomic hybridization (aC GH) and fluorescence in situ hybridization. There were 11 males and 10 females, ranging in age from 53 to 79 years old. The diameter of tumor ranged from 1.5 to 16 cm. Follow-up information was obtained in 14 patients (1-96 months of follow-up). Metastatic dissemination was found in 5 cases. All tumors are composed of two cell populations, arranged in an organ-like structure: the lack of cytoplasm, small low-grade tumor cells usually lined inside the alveolar structure, and