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目的:探讨脱落细胞学和肿瘤标志物联合检查在恶性胸腹水临床诊断中的应用价值。方法:选取我院2012年2月-2014年2月收治的176例恶性胸腹水患者,采取脱落细胞学和肿瘤标志物联合检查,分析其临床检测效果。结果:单纯应用脱落细胞学检查恶性胸腹水阳性率61.9%,脱落细胞学联合癌胚抗原(CEA)阳性率为92.0%,脱落细胞学检查联合CEA、糖蛋白抗原199(CA199)阳性率为96.0%。结论:脱落细胞学和肿瘤标志物联合检查恶性胸腹水具有较高阳性率和准确率,临床应用价值较高。
Objective: To investigate the value of combined detection of cytology and tumor markers in the clinical diagnosis of malignant pleural effusion. Methods: A total of 176 patients with malignant ascites and pleural effusion admitted from February 2012 to February 2014 in our hospital were enrolled. Combined with exfoliative cytology and tumor markers, the clinical efficacy of the test was analyzed. Results: The positive rate of exfoliative cytology in malignant pleural effusion and ascites was 61.9%. The positive rate of exfoliative cytology combined with carcinoembryonic antigen (CEA) was 92.0%. The positive rate of exfoliative cytology combined with CEA and glycoprotein antigen 199 (CA199) was 96.0 %. Conclusion: Combined cytology and tumor markers in malignant pleural effusion with a higher positive rate and accuracy, higher clinical value.