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目的:探究高压氧辅助微创钢板内固定术治疗胫骨中下段骨折的疗效，并分析其对骨折处皮肤血运的影响。方法:选取2016年1月至2018年12月入住沈阳市第四人民医院院骨一科的100例胫骨中下段骨折患者作为研究对象，按随机数字表法将其分为对照组(n n＝50)和观察组(n n＝50)。对照组患者给予微创钢板内固定术治疗，观察组在对照组治疗的基础上辅助高压氧治疗，连续治疗4周。比较术后1周、术后1个月及6个月2组患者疼痛视觉模拟评分(VAS)、骨折处皮肤血运情况、骨折愈合情况、骨密度及膝、踝关节功能。n 结果:术后1周，观察组和对照组VAS、骨折愈合结痂评分、骨密度差异均无统计学意义(n P>0.05)。术后1个月，观察组患者VAS、骨折愈合结痂评分及骨密度均优于对照组(n P0.05). One month after surgery, the VAS score, the score of fracture healing and scabbing, and the bone density of the observation group were significantly better than those of the control group (n P<0.05). In the observation group, the incidence of poor blood supply to the skin at the fracture site was 14.0%, which was significantly lower than that of the control group (32.0%) (n P<0.05). The recovery rate of the function of knee and ankle joints was 58.0%, which was higher than that in the control group (38.0%) (n P<0.05). Six months after surgery, the VAS score of the observation group was significantly decreased, and the bone density in the observation group was significantly increased, compared with those of the control group. All differences were statistically significant (n P0.05).n Conclusion:Hyperbaric oxygen assisting minimally invasive plate osteosynthesis in treating the middle and distal tibia fracture could increase the partial pressure of blood oxygen, accelerate the revascularization at the fracture site, reduce local tissue edema and necrosis, promote bone healing, and reduce postoperative pain, which could be used as an auxiliary treatment for the middle and distal tibial fracture.